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β-Glycyrrhetinic acid - 9586-1G - 1 g - BioVision - small molecule compounds

β-Glycyrrhetinic acid
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Size: 1 g
£84.00
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Catalogue number:
9586-1G
Name:
β-Glycyrrhetinic acid
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β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. It inhibits 15-PGDH (15-hydroxyprostaglandin dehydrogenase) leading to increased prostaglandin concentration in the digestive system. Displays anti-ulcerative, anti-inflammatory, and immunomodulatory properties. In addition, β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC₅₀ values of 16.1, 19.3, 15.8, and 13.7 µM, respectively. Also protects liver against the toxic effect of chemotherapeutic alkylating agents via activation of Nrf2 (NF-E2-related factor-2) and PPARγ.

Data sheet:

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Product Type:
Small Molecule Compounds
CAS Number:
471-53-4
Alternative Names:
3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid, Enoxolone; STX352; GM1658; NSC 35347
Storage Temp:
-20°C
Compound Purity:
≥97% by titration
Molecular Weight:
471
Structure:
https://www.biovision.com/media/catalog/product/9/
UNSPSC Code:
12352100
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