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CAS Number:
1633044-56-0
Purity:
≥98% by HPLC
Molecular Weight:
634
Alternative Names:
N-(4-((3-(3,5-dimethoxyphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
FIIN-2 is a potent, selective, irreversible, next-generation covalent FGFR inhibitor. FIIN-2 is the first inhibitor that can potently inhibit the proliferation of cells dependent upon the gatekeeper mutants of FGFR1 or FGFR2, which confer resistance to first-generation clinical FGFR inhibitors such as NVP-BGJ398 and AZD4547.
Storage Temperature:
-20°C