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AMG-232

Supplier:
Catalogue number:
9556-5
Size:
5 mg
Product is available in:
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AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).

Product Type:

Small Molecule Compounds

CAS Number:

1352066-68-2

Alternative Names:

2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-propan-2-ylsulfonylbutan-2-yl]-2-oxopiperidin-3-yl]acetic acid

Storage Temp:

-20°C

Compound Purity:

≥98% by HPLC

Molecular Weight:

568.55

UNSPSC Code:

12352100

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