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CAS Number:
1352066-68-2
Purity:
≥98% by HPLC
Molecular Weight:
568
Alternative Names:
2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-propan-2-ylsulfonylbutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).
Storage Temperature:
-20°C
