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STF-118804 - 9552-25 - 25 mg - BioVision - small molecule compounds

STF-118804
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Size: 25 mg
£632.00
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Catalogue number:
9552-25
Name:
STF-118804
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STF-118804 is a potent and highly specific inhibitor of Nampt (nicotinamide phosphoribosyl transferase) (IC₅₀s = 3-6 nM) that prevents NAD⁺ synthesis from nicotinamide. It inhibits the viability of multiple B-cell acute lymphoblastic leukemia (B-ALL) cell lines with nanomolar potency and induces apoptosis in MV411 cells. It improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia, and targets leukemia stem cells.

Data sheet:

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Product Type:
Small Molecule Compounds
CAS Number:
894187-61-2
Alternative Names:
4-(5-methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide
Storage Temp:
-20°C
Compound Purity:
≥98% by HPLC
Molecular Weight:
462
Structure:
https://www.biovision.com/media/catalog/product/9/
UNSPSC Code:
12352100
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