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TLR5(Toll-like receptor 5) Polyclonal Antibody - 3555-100 - 100 µg - BioVision - antibodies

TLR5(Toll-like receptor 5) Polyclonal Antibody
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Size: 100 µg
£377.00
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Catalogue number:
3555-100
Name:
TLR5(Toll-like receptor 5) Polyclonal Antibody
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The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology(TH) domain,which is essential for Toll-induced signal transduction.TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride(LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB Signaling upon activation. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.

Data sheet:

Click to view / download

Applications:

Western blot

Product Type:
Antibodies
Alternative Names:
Toll Like Receptor 5
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthetic peptide surrounding amino acid 330 of human TLR5
Storage Temp:
-20°C
Antibody Host:
Rabbit
Antibody Isotype:
rabbit IgG
Antibody Type:
Polyclonal
UNSPSC Code:
12352203
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