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NIK Antibody - 3193-100 - 100 µg - BioVision - antibodies

NIK Antibody
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Size: 100 µg
£314.00
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Catalogue number:
3193-100
Name:
NIK Antibody
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Availability:

NIK (NF-kB-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-kB activity. NIK was initially isolated from a human B cell cDNA library and contains 795 amino acids with an apparent molecular_weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to IkB phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-kB activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-kB activation.

Data sheet:

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Applications:

Western blot

Product Type:
Antibodies
Alternative Names:
MAP3K14
Species Reactivity:
Human
Immunogen:
E. coli expressed recombinant human NIK fragment (a.a. 795-947).
Storage Temp:
-20°C
Antibody Host:
Rabbit
Antibody Isotype:
Rabbit IgG
Antibody Type:
Polyclonal
UNSPSC Code:
12352203
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