£153.00
Estimated delivery Tue 30 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
956905-27-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
372.4
Alternative Names:
4-[1-(6-quinolinylmethyl)-1h-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1h-pyrazole-1-ethanol
- Data sheet: View or download
- MSDS: View or download
Product Description:
A c-Met inhibitor (Ki = 4.8 nM); >1,000-fold selective for c-Met over a panel of 150 kinases; inhibits the proliferation of and induces apoptosis in GTL-16 cells (IC50s = 12 and 31 nM, respectively); inhibits HGF-induced migration of H441 cells (IC50 = 11 nM); reduces tumor growth in a GTL-16 mouse xenograft model at 1-30 mg/kg
Storage Temperature:
-20°C
