£323.00
Estimated delivery Tue 9 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
936890-98-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
406.4
Alternative Names:
trans-4-[4-amino-5-(7-methoxy-1h-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-cyclohexanecarboxylic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of the catalytic site of mTOR, inhibiting both mTORC1 and mTORC2 (IC50s = 22 and 65 nM, respectively); prohibits proliferation, induces autophagy, and potentiates apoptosis in BCR-ABL transformed cells and other cancer cells at 10 µM; effective in vivo
Storage Temperature:
-20°C