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AZD 1480

Catalogue number:
CAY10702-50 mg
Supplier:
Size:
50 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£1117.00 Estimated delivery Tue 9 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

935666-88-9

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

348.8

Alternative Names:

5-chloro-n2-[(1s)-1-(5-fluoro-2-pyrimidinyl)ethyl]-n4-(5-methyl-1h-pyrazol-3-yl)-2,4-pyrimidinediamine

Product Description:

A selective JAK2 inhibitor that blocks signaling (IC50 = 58 nM at 5 mM ATP) and proliferation of JAK2-expressing cell lines (GI50 = 60 nM); displays good pharmacokinetics in vivo, inhibits STAT3 and STAT5 activation in vivo, and suppresses tumorigenesis in mouse xenografts harboring constitutive STAT3 activity

Storage Temperature:

-20°C

CAY10702-50 mg: AZD1480
CAY10702-50 mg: AZD1480
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