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SensoLyte® AMC tPA Activity Assay Kit *Fluorimetric* - ANA72160 - 1 kit - AnaSpec - assays & kits

SensoLyte® AMC tPA Activity Assay Kit *Fluorimetric*
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Size: 1 kit
£649.00
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Catalogue number:
ANA72160
Name:
SensoLyte® AMC tPA Activity Assay Kit *Fluorimetric*
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Tissue-type plasminogen activator (tPA) is a serine protease that cleaves pro-enzyme plasminogen into active plasmin. It has been recognized that tPA play important roles in various physiological and pathological processes. In plasma, it functions as a thrombolyticEnzyme and can be used for treatment of ischemic stroke. In the central nervous system, tPA promotes events associated with synaptic plasticity and cell death in a number of settings, such as cerebral ischemia and seizures. The SensoLyte® AMC tPA Activity Assay Kit is optimized for assaying tPAEnzyme activities. This kit contains a fluorogenic substrate with a high reactivity and low background. tPA cleaves the substrate resulting in release of AMC (7-amino-4-methylcoumarin) fluorophore. Fluorescence can be monitored at excitation /emission= 354/442 nm. This kit can be used for high throughput screening of tPA inducers and inhibitors.

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Product Type:
Assays & Kits
UNSPSC Code:
12352202
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