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Methoxyresorufin

Supplier:
Catalogue number:
ANA85707
Size:
5 mg
Product is available in:
  • UK
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Fluorogenic cytochrome P-450 substrate that generates red fluorescent product uponEnzyme cleavag

Product Type:

Reagents & Kit Components

Storage Temp:

-20°C desiccated and protected from light

Molecular Weight:

227.2

Reference:

Donato MT, et al. (2004). Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes. Drug Metab Dispos 32, 699-706, Liu J, et al. (2004). The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism. Arch Biochem Biophys 424, 33-43, Chougnet A, et al. (2003). Design and synthesis of a new fluorescent probe for cytochrome P450 3A4 (CYP 3A4). Bioorg Med Chem Lett 13, 3643-5, Dunn AR, et al. (2002). Fluorescent probes for cytochrome P450 structural characterization and inhibitor screening. J Am Chem Soc 124, 10254-5, Nakamura K, et al. (2001). Coumarin substrates for cytochrome P450 2D6 fluorescence assays. Anal Biochem 292, 280-6, Thapliyal R and Maru GB (2001). Inhibition of cytochrome P450 isozymes by curcumins in vitro and in vivo. Food Chem Toxicol 39, 541-7, Roser R and Thomas H (2000). A direct, highly sensitive fluorimetric assay for a microsomal cytochrome P450-mediated O-demethylation using a novel coumarin analog as substrate. Z Naturforsch [C] 55, 915-22, Kobayashi Y, et al. (1998). Probing the active site of cytochrome P450 2B1: metabolism of 7-alkoxycoumarins by the wild type and five site-directed mutants. Biochemistry 37, 6679-88.

UNSPSC Code:

12352200

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