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SensoLyte® 440 Cathepsin S Assay Kit, Fluorimetric

Supplier:
Catalogue number:
ANA72100
Size:
1 kit
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£632.00 Shipping is calculated in checkout

Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin S is a cysteine proteinase involved in the pathogenesis of autoimmune diseases, atherosclerosis,Cancer, obesity and related diseases. The SensoLyte® 440 Cathepsin S Assay Kit uses a fluorogenic peptide for measurement ofEnzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin S cleavage, and which can be detected with excitation at 354 nm and emission at 442 nm. The kit contains: , AMC based fluorogenic substrate (Ex/Em=354 nm/442 nm upon cleavage) , Assay buffer , Human spleen Cathepsin S , Inhibitor , Fluorescence reference standard for calibration , A detailed protocol

Product Type:

Assays & Kits

Storage Temp:

Component C at -80°C, all other components at -20°C

UNSPSC Code:

41116012