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SensoLyte® 390 ACE2 Activity Assay Kit *Fluorimetric*

Supplier:
Catalogue number:
ANA72086
Size:
1 kit
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£665.00 Shipping is calculated in checkout

ACE2 or ACEH, angiotensin-convertingEnzyme 2, a homolog of angiotensin-convertingEnzyme, is a novel zinc metallopeptidase with specificity, tissue distribution, and function distinct from those of ACE. ACE2 may play a unique role in the renin-angiotensin system and mediate cardiovascular and renal function. The SensoLyte® 390 ACE2 Activity Assay Kit provides a convenient assay for high throughput screening of ACE2Enzyme inhibitors and inducers using a Mc-Ala/Dnp fluorescence resonance energy transfer (FRET) peptide. In the FRET peptide, the fluorescence of Mc-Ala is quenched by Dnp. Upon cleavage into two separate fragments by ACE2, the fluorescence of Mc-Ala is recovered, and can be monitored at excitation/emission = 330/390 nm. This assay can detect the activity of subnanogram level of ACE2. Assays are performed in a convenient 96-well microplate format.

Product Type:

Assays & Kits

Storage Temp:

-20°C

UNSPSC Code:

41116012