Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Over 40,000 Peptides & Proteins Available
Highly Sensitive, Low Abundance Target Detection In ICC, IHC & FISH
Find Your Peptide Simply with Our Peptide Search

Receive High Quality Leukaemia & Lymphoma Biospeciemens Within 24 Hours

 

SensoLyte® 520 MMP - 14 Assay Kit *Fluorimetric* - ANA72025 - 1 kit - AnaSpec - assays & kits

SensoLyte® 520 MMP - 14 Assay Kit *Fluorimetric*
print page
Size: 1 kit
£650.00
GBP | Euro | USD
Add to basket
Catalogue number:
ANA72025
Name:
SensoLyte® 520 MMP - 14 Assay Kit *Fluorimetric*
Supplier:
Availability:

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-14 (MT1-MMP) is the membrane bound MMP. When expressed in cells, the catalytic and the hemopexin domains of MMP-14 become exposed on cell surfaces. ThisEnzyme plays an important role in tumor invasion. SensoLyte® 520 MMP-14 Assay Kit uses a 5-FAM (fluorophore) and QXL®520 (quencher) labeled FRET peptide substrates for continuous measurement of theEnzyme activities. In an intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL® 520. Upon the cleavage of the FRET peptide by MMP-14, the fluorescence of 5-FAM is recovered, and can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, 5-FAM/QXL®520 based FRET peptide is less interfered by the autofluorescence of test compounds and cellular components and provides better assay sensitivity. The assays are performed in a convenient 96-well or 384-well microplate format.

Data sheet:

Click to view / download

Product Type:
Assays & Kits
Storage Temp:
-20°C
UNSPSC Code:
41116012
Contact Our Friendly Technical Team