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Beta-Amyloid (11-25), Human

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Catalogue number:
ANA62884
Size:
1 mg
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This amino acids 11 to 22 fragment of b-amyloid is capable of forming well-organized amyloid fibrils in vitro, similar to the pathogenic ones found in amyloidosis. Analysis of the structural properties of one monomer of b-amyloid (11-22) as well as of the aggregation mechanisms for four chains of b-amyloid (11-22) showed that the system assembles rapidly into a random globular state that evolves into three- and four-stranded antiparallel beta-sheets. The aggregation process is considerably accelerated by the presence of preformed dimers.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

1755

Reference:

Boucher, G. et al. Proteins 65, 877 (2006); Tjernberg, L. et al. J. Biol. Chem. 274, 12619 (1999).

UNSPSC Code:

12352202