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Glutamic Acid Decarboxylase (GAD65) (524-543), p524-543 - ANA62757 - 1 mg - AnaSpec - proteins & peptides

Glutamic Acid Decarboxylase (GAD65) (524-543), p524-543
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Size: 1 mg
£173.00
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Catalogue number:
ANA62757
Name:
Glutamic Acid Decarboxylase (GAD65) (524-543), p524-543
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This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.

Data sheet:

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Product Type:
Proteins & Peptides
Alternative Names:
SRLSKVAPVIKARMMEYGTT
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2238.7
Reference:
Quinn, A. et al. J. Immunol. 166, 2982 (2001); Dai, Y. et al. J. Immunol. 175, 3621 (2005).
UNSPSC Code:
12352200
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