MOG (92–106)

This is amino acids 92 to 106 fragment of the myelin oligodendrocyte glycoprotein (MOG). Mice with MOG (92–106)-induced experimental autoimmune encephalomyelitis develop extensive B cell reactivity against secondary myelin antigens. Despite the fact that this MOG peptide induces only weak T cell responses, MOG-inducedAutoimmunity is very severe. This peptide is encephalitogenic in SJL mice, DA rats, and rhesus monkeys.