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PUMA BH3

Supplier:
Catalogue number:
ANA62404
Size:
1 mg
Product is available in:
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This is a PUMA (p53 upregulated modulator of apoptosis) BH3 domain peptide. PUMA together with Bcl-xL, and cytoplasmic p53 coordinates p53 functions. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

3049.3

Reference:

Chipuk, J. et al. Science 309, 1732 (2005), Nakano, K. et al. Mol. Cell 7, 683 (2001), Yu, J. et al. Mol. Cell 7, 673 (2001), Han, J. et al. Proc. Natl. Acad. Sci. U S A. 98, 11318 (2001).

UNSPSC Code:

12352202

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