Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Fast & Sensitive Prostaglandin E2 EIA
Find Your Peptide Simply with Our Peptide Search
Over 40,000 Peptides & Proteins Available

Receive High Quality Leukaemia & Lymphoma Biospeciemens Within 24 Hours

 

Rat Renin FRET Substrate (5-FAM/QX® 520) - ANA62334-01 - 0.1 mg - AnaSpec - proteins & peptides

Rat Renin FRET Substrate (5-FAM/QX® 520)
print page
Size: 0.1 mg
£313.00
GBP | Euro | USD
Add to basket
Catalogue number:
ANA62334-01
Name:
Rat Renin FRET Substrate (5-FAM/QX® 520)
Supplier:
Availability:

This renin FRET peptide is a specific substrate for rat renin. Aspartyl protease cleaves angiotensinogen to yield angiotensin I, which is further converted to angiotensin II. The renin-angiotensin system is a coordinated hormonal cascade in the control of cardiovascular, renal, and adrenal function. It governs body fluid and electrolyte balance, as well as arterial pressure. Since an overactive renin-angiotensin system leads to hypertension, renin is an attractive target for the treatment of this disease. This renin peptide substrate may be used for screening renin inhibitors. In the FRET peptide, the fluorescence of 5-FAM is quenched by QXL® 520. Upon cleavage into two separate fragments by rat renin, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission = 490/520 nm. The SensoLyte® 520 Renin Assay Kit (cat # 72040) contains the human renin FRET substrate.

Data sheet:

Click to view / download

Product Type:
Proteins & Peptides
Species Reactivity:
Immunogen:
Storage Temp:
-20°C
Antibody Host:
Antibody Isotype:
Antibody Type:
Clone Number:
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2000
Material Safety Data Sheet:
Reference:
Sample Type:
Structure:
UNSPSC Code:
12352202
Contact Our Friendly Technical Team
Lipocalyx - Novel Active Endosome Escape Based Transfection Reagents