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Bax BH3 peptide (55-74), wild type

Supplier:
Catalogue number:
ANA62266
Size:
1 mg
Product is available in:
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This is a 20–amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

2267.6

Reference:

Shangary, S. et al. Mol. Canc. Ther. 3, 1343 (2004); Shangary, S. et al. Biochem. 41, 9485 (2002).

UNSPSC Code:

12352202