Bax BH3 peptide (55-74), wild type
Supplier:
Catalogue number:
ANA62266
Size:
1 mg
Product is available in:
This is a 20–amino acid Bax BH3 peptide (Bax 1) capable of inducing apoptosis in a variety of cell line models. In addition to disrupting Bax/Bcl-2 and Bax/Bcl-XL, it can promote cytochrome c release from isolated mitochondria. Bax BH3 belongs to the Bcl-2 protein family which consists of both pro-apoptotic and anti-apoptotic members. Bax BH3 acts to regulate apoptosis via governance of the 'intrinsic' pathway of cell death.
Product Type:
Proteins & Peptides
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2267.6
Reference:
Shangary, S. et al. Mol. Canc. Ther. 3, 1343 (2004); Shangary, S. et al. Biochem. 41, 9485 (2002).
UNSPSC Code:
12352202
Proteins & Peptides from AnaSpec: