This is the pro-apoptotic peptide composed of D-amino acids, 5-FAM labeled. This alpha-helical amphipathic peptide is toxic to eukaryotic cells if internalized by a suitable targeting mechanism. It disrupts mitochondrial membranes upon receptor-mediated cell internalization and causes programmed cell death.
Proteins & Peptides
Peak Area by HPLC ≥95%
Marks, A. et al. Cancer Res. 65, 2373 (2005); Kolonin, M. et al. Nat. Med. 10, 625 (2004).