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LyP-1, Peptide 1

Supplier:
Catalogue number:
ANA62169
Size:
1 mg
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LyP-1 recognizes lymphatics and tumor cells in certain tumors, but not lymphatics in normal tissues. Screening on breast carcinoma xenografts shows positive to cyclic 9-amino-acid peptide, LyP-1. The LyP-1 also recognizes an osteosarcoma xenograft, and spontaneous prostate and breastCancers in transgenic mice. LyP-1 peptide is detected in tumor structures that are positive for several lymphatic endothelial markers and negative for blood vessel markers. LyP-1 accumulates in the nuclei of the putative lymphatic cells, and in the nuclei of tumor cells.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

992.2

Reference:

Zhang, L. et al. Canc. Res. 66, 5696 (2006); Akerman, M. et al. PNAS 99, 12617 (2002); Laakkonen, P.et al. Nat. Med. 8, 751 (2002).

UNSPSC Code:

12352202