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Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled - ANA62152 - 1 mg - AnaSpec - proteins & peptides

Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled
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Size: 1 mg
£345.00
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Catalogue number:
ANA62152
Name:
Steroid Receptor Coactivator-1 (SRC-1), (676-700), biotin labeled
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Signal Transduction Peptides

Data sheet:

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Product Type:
Proteins & Peptides
Alternative Names:
Biotin-CPSSHSSLTERHKILHRLLQEGSPS
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
3026.5
Reference:
This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain.
UNSPSC Code:
12352202
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