SRC-1 (676-700), Biotin
Catalogue number:
ANA62152
Supplier:
Size:
1 mg _$$_
Product is available in:
£449.00
Estimated delivery Thu 25 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
3026.6
Product Description:
This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminal biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic beta-helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain.
Storage Temperature:
-20°C