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[Gly21]-beta-Amyloid (1-40), A21G, Flemish Mutation, Human

Supplier:
Catalogue number:
ANA62150
Size:
0.5 mg
Product is available in:
  • UK
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This peptide is the mutant form of the b-Amyloid peptide (1-40). The mutation within the coding region of the β-Amyloid precursor protein (APP) results in substitution of glycine for alanine in this peptide. Presenile dementia is present in a pattern consistent in the family of British origin with the dominant inheritance of Flemish APP mutation. The impact of the point mutation A21G on b-Amyloid structure and dynamics varies from b-Amyloid (1-40) to b-Amyloid (1-42).

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

4315.9

Reference:

Brooks, W. et al. Neurol. 63, 1613 (2004); Van Nostrand, W. et al. J. Biol. Chem. 276, 32860 (2001); A. Huet and P. Derreumaux Biophys. J. 91, 3829 (2006).

UNSPSC Code:

12352202

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