[Asn23]-beta-Amyloid (1-40), Iowa Mutation, Human - ANA62145 - 0.5 mg - AnaSpec - proteins & peptides

This peptide is naturally occurring mutant within the beta-amyloid region of b-amyloid protein precursor (APP). This mutation is associated with severe cerebral amyloid beta-protein angiopathy (CAA) in Iowa kindred. The affected individuals share a missense mutation in APP at position 694. This site corresponds to residue 23 of beta-amyloid peptide resulting in substitution of asparagine for aspartic acid.

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