Pannexin-1 (Panx1), Mimetic Blocking Peptide - ANA61911 - 1 mg - AnaSpec - proteins & peptides
Pannexin-1 (Panx1), Mimetic Blocking Peptide
Catalogue number:
ANA61911
Name:
Pannexin-1 (Panx1), Mimetic Blocking Peptide
Supplier:
Availability:
This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1? (IL-1?) in response to P2X7R activation.
Data sheet:
Product Type:
Proteins & Peptides
Alternative Names:
WRQAAFVDSY
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
1242.4
Reference:
Pelegrin, P. et al. EMBO. J. 25, 5071 (2006); Pelegrin, P. et al.t J. Biol. Chem. 282, 2386 (2007).
UNSPSC Code:
12352202
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