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Cys(Npys)-(Arg)9 - ANA61205 - 1 mg - AnaSpec - proteins & peptides

Cys(Npys)-(Arg)9
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Size: 1 mg
£319.00
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Catalogue number:
ANA61205
Name:
Cys(Npys)-(Arg)9
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This is a peptide comprising of 9 Arginine residues and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group protects cysteine. This kind of modification has been used to render this peptide as a carrier peptide applicable in conjugation and cell permable studies. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond. Coupling of sulfhydrils has been studied as an effective means to deliver/release therapeutics such as siRNA in the reducing environment within the cell. For example, in a study leukemic-specific SiRNA was delivered by the formation of immunocomplexes that consisted of targeted antibody conjugated to oligo-9-Arg peptides.

Data sheet:

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Product Type:
Proteins & Peptides
Alternative Names:
C(Npys)RRRRRRRRR-NH2
Storage Temp:
-20°C
Molecular Weight:
1680.1
Reference:
Lee KY. et al. Mol & Cells. 29(5):457-462 (2010).
UNSPSC Code:
12352202
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