*

Fibrinopeptide B, human

Supplier:
Catalogue number:
ANA60697
Size:
1 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£89.00 Shipping is calculated in checkout

The fibrinopeptide B is an N-terminal modified peptide with pyroglutamylation, one of the common post-translational process. In one of the final steps in the coagulation pathway, thrombin converts soluble fibrinogen to fibrin by first cleaving off FPA to form fibrin I, which spontaneously polymerizes. Thrombin then releases fibrinopeptide B (FPB) from the beta-chains of the fibrin I subunits to form fibrin II polymers, which associate and cross-links to form a semi-solid network, while the fibrinopeptides remain soluble in plasma. Fibrin formation associated with active thrombosis leads to significantly higher plasma levels of FPB and thus measurement of plasma FPB levels is a more sensitive and specific serologic marker for acute thrombosis.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

1553.6

Reference:

Mikami and Takao. Anal. Chem. 79:7910-7915 (2007).

UNSPSC Code:

12352202

Sorry - there are no images available for this product.