Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB. It displays similar specificities towards PKB α, PKBβ and PKBγ isoforms. It is also recognized by MAPKAP kinase-1 and p70S6K. The fluorescent and biotinlyated peptides demonstrate similarEnzyme activities.
Proteins & Peptides
Peak Area by HPLC ≥95%
Ref: Dai, F. et al. Biochem. Biophys. Res. Commun. 293, 1191 (2002). Meier, R. et al. J. Biol. Chem. 272, 30491 (1997); Chan, TO. et al. Ann. Rev. Biochem. 68, 965 (1999).