Tel: +44 (0)1223 316 855
life science research products, biological research products, biotechnology
close ...


Supplier:
Product types:
Find Your Peptide Simply with Our Peptide Search
Over 40,000 Peptides & Proteins Available
Same Day Delivered Fresh Human Blood

Assemble DNA Constructs Simply & Efficiently Using The Gibson Assembly® Method

NGR Peptide 1 - ANA60189-1 - 1 mg - AnaSpec - proteins & peptides

NGR Peptide 1
print page
Size: 1 mg
£313.00
GBP | Euro | USD
Add to basket
Catalogue number:
ANA60189-1
Name:
NGR Peptide 1
Supplier:
Availability:

This is a peptide with NGR (Asn-Gly-Arg) motif having a disulfide bridge connecting cys1 to cys5 known to elicit antimicrobial property in addition to the presence of KLA sequence. This peptide shows potent cytotoxicity and activity against tumor cells due to its binding to CD13 on tumor cells. This peptide shows dose-dependent antiproliferation against tumor cells and induces cell cylce arrest at G2/M phases and apoptosis of the tumor cells. NGR motif containing peptides are useful in delivering cytotoxic drugs, proapoptotic peptides and tumor necrosis factor (TNF) to tumor vasculature.

Data sheet:

Click to view / download

Product Type:
Proteins & Peptides
Alternative Names:
CNGRCGGklaklakklaklak-NH2 (Disulfide bridge: 1-5)
Storage Temp:
-20°C
Molecular Weight:
2168.7
Reference:
1, Ellerby, HM. et al. Nat Med. 5, 1032 (1999) 2, Colombo, G. et al. J. Biol. Chem. 277, 47891 (2002) 3, Van Hensbergen, Y. et al. Biochem. Pharmacol. 63, 897 (2002) 4, Plesniak, L. et al. Protein Sci. 13, 1988 (2004) 5, Zhang Z. et al. Tum Biol. 36(10), 8167-8175 (2015).
UNSPSC Code:
12352202
Contact Our Friendly Technical Team