www.bioscience.co.uk
Sales & Support: +44 (0)1223 316 855

*

Azurocidin, Human, mAb z6733

Catalogue number:
Supplier:
Size:
100 µg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
N/A
Shipping is calculated in checkout
This product is no longer available to order.
Applications:

IA

Antibody Host:

Mouse

Antibody Isotype:

IgG1

Antibody Type:

Monoclonal antibody

Alternative Names:

Cationic antimicrobial peptide CAP37, Heparin-binding protein, HBP

Product Description:

The monoclonal antibody z6733 recognizes azurocidin (also called heparin-binding protein (HBP) or cationic antimicrobial protein of 37 Kda (CAP37). Azurocidin is an inactive homolog of serine proteinases residing in granulocytes. Initially it was thought to have only activity against gram-negative bacteria. Later it was also found to act against gram-positive bacteria and C.albicans. Azurocidin is considered a family member of polymorphonuclear leukocytes- derived antimicrobial proteins like defensins, LL-37 and lysozyme. Azurocidin has been recognized as a player in the activation and modulation of the immune response and may act to alarm the immune system. The cationic domain at one side of the protein is essential for its antimicrobial activity. It is stored in azurophil granules as well as secretory granules and as a result partly released at early stage of extravasation. Azurocidin is involved in chemotaxis and activation of monocytes, cytokine release and phagocytosis leading to more efficient bacterial clearance. The primary targeted environment of azurocidin are cells in the bloodstream, that is the endothelial lining, and the extravascular surroundings. The interaction of azurocidin with leucocytes is mediated via β2-intergrins. High plasma levels of azurocidin might help with the identification of patients which are at risk in developing sepsis.

Storage Temperature:

2 - 8°C

HM2311 Azurocidin, Human, mAb z6733
HM2311 Azurocidin, Human, mAb z6733
Details Cat number & supplier Size Price
TLR4, Human, mAb HTA125, PE HM2068PE-100 · Hycult Biotech
HM2068PE-100
Hycult Biotech
100 tests £382.00
100 tests
view
TLR4, Human, mAb HTA125, PE HM2068PE-25 · Hycult Biotech
HM2068PE-25
Hycult Biotech
25 tests £194.00
25 tests
view
IFN-alpha, Mouse, mAb F18 HM1001-20UG · Hycult Biotech
HM1001-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
IFN-gamma, Mouse, mAb F3 HM1002-20UG · Hycult Biotech
HM1002-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
IFN-gamma, Mouse, mAb F1 HM1003-20UG · Hycult Biotech
HM1003-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
IL-6, Mouse, mAb MP5-20F3 HM1004-20UG · Hycult Biotech
HM1004-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
IL-6, Mouse, mAb MP5-32C11 HM1005-20UG · Hycult Biotech
HM1005-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
TNF-RI, Mouse, mAb HM104 HM1009-20UG · Hycult Biotech
HM1009-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
TNF-RI, Mouse, mAb HM104, FITC HM1009F-20UG · Hycult Biotech
HM1009F-20UG
Hycult Biotech
20 µg £132.00
20 µg
view
TNF-RII, Mouse, mAb HM102 HM1011-20UG · Hycult Biotech
HM1011-20UG
Hycult Biotech
20 µg £132.00
20 µg
view