Aβs are generated by the proteolytic processing of the amyloid β-precursor protein (APP). Subsequent cleavage by g-secretase gives rise to Aβ (1-40/42) and Aβ (11-40/42). Aβ (11-40) and Aβ (11-42) are major Aβ cleavage products generated by BACE.
Proteins and peptides
Peak Area by HPLC ≥95%
Liu, K. et al. Biochem. 41, 3128 (2002).