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390 MMP FRET Substrate I - ANA27077 - 5 mg - AnaSpec - proteins & peptides

390 MMP FRET Substrate I
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Size: 5 mg
£508.00
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Catalogue number:
ANA27077
Name:
390 MMP FRET Substrate I
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A fluorogenic substrate that is best cleaved by MMP-7, 8, 9 and 13. The highly fluorescent Mca moiety is efficiently quenched by energy transfer to the Dnp group. The punctuated metallo proteinase (PUMP, EC 3.4.24.23) cleaves the substrate at the Gly-Leu bond with a 190-fold increase in fluorescence (Abs/Em = 325/393 nm). In human matrix metalloproteinases assays, this substrate is about 50 to 100 times more sensitive than the generic MMP substrate, Dnp-PLGLWAr-NH2 (Cat# 27074).

Data sheet:

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Product Type:
Proteins & Peptides
Alternative Names:
Mca-PLGL-Dpa-AR-NH2
Storage Temp:
-20°C
Molecular Weight:
1093.2
Reference:
Knight, CG. et al. FEBS Lett. 296, 263 (1992); Netzel-Arnett, S. et al. Anal. Biochem. 195, 86 (1991).
UNSPSC Code:
12352202