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Angiotensin II Substrate

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Catalogue number:
ANA24520
Size:
1 mg
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This is a tyrosine phosphorylated angiotensin II peptide with a substrate sequence specificity for chymase to act. This is an octapeptide hormone that is formed as a result of the action of human heart chymase, a chymotrypsin-like serine protease on the Phe-His bond of Angiotensin I. The ideal susbtrate for human heart chymase should contain this peptide sequence, and has been demonstrated that the Pro-Phe sequence in P2-P1 positions of peptide substrates is highly favored by leukocyte chymotrypsin-like proteinases such as chymases and cathepsin G.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

1126.2

Reference:

1, Kinoshita A, et al. J Biol Chem 266(29): 19192-19197 (1991). 2, Ruzzene, M. et al. Eur. J. Biochem. 211, 289 (1993).

UNSPSC Code:

12352202

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