Peak Area by HPLC ≥95%
4470
%3Cp%3EThis%20is%20fluorescent%20GLP-1%20labeled%20at%20the%20peptide%20N-terminus%20with%20FAM%2C%20Abs/Em%3D494/521%20nm.%20In%20response%20to%20Glucose%20ingestion%2C%20proglucagon%20in%20the%20intestinal%20L%20cells%20is%20cleaved%20into%20GLP-1%20%281-36%29.%20Prior%20to%20secretion%20into%20the%20circulation%2C%20GLP-1%20%281-36%29%20is%20further%20processed%20into%20amidated%20GLP-1%20%287-36%29-and%20small%20amounts%20of%20glycine-extended%20GLP-1%20%287-37%29.%20Both%20GLP-1%20%287-36%29%20and%20GLP-1%20%287-37%29%2C%20causes%20glucose%20dependent%20release%20of%20insulin%20by%20pancreatic%20beta-cells.%20They%20also%20play%20a%20role%20in%20gastric%20motility%20%28gastric%20emptying%29%2C%20on%20the%20suppression%20of%20plasma%20glucagon%20levels%20%28glucose%20production%29%20and%20possibly%20on%20the%20promotion%20of%20satiety%20and%20stimulation%20of%20glucose%20disposal%20in%20peripheral%20tissues%20independent%20of%20the%20actions%20of%20insulin.%20GLP-1%20peptides%20such%20as%20GLP-1%20%281-36%29%20have%20been%20used%20to%20investigate%20restoration%20of%20pancreatic%20beta%20cell%20function.%20GLP-1%20is%20also%20produced%20in%20the%20central%20nervous%20system.%3Cbr%3E%3C/p%3E
-20°C Darkness