Endothelin 1, human, porcine - ANA22861 - 1 mg - AnaSpec - proteins & peptides
Endothelin 1, human, porcine
Catalogue number:
ANA22861
Name:
Endothelin 1, human, porcine
Supplier:
Availability:
ET-1 is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes.
Data sheet:
Product Type:
Proteins & Peptides
Alternative Names:
CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: 1-15 and 3-11)
Storage Temp:
-20°C
Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2492
Reference:
Ref: Yanagisawa, M. et al. Nature. 332, 411 (1988).
UNSPSC Code:
12352202
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