£334.00
Estimated delivery Thu 25 Apr
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Shipping is calculated in checkout
CAS Number:
117399-94-7
Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
2492
Product Description:
ET-1 is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes.
Storage Temperature:
-20°C