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Endothelin 1, human, porcine

Supplier:
Catalogue number:
ANA22859
Size:
0.25 mg
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ET-1 is a potent vasoconstrictor peptide derived from endothelial cells. It plays a role in regulation of cardiovascular functions. The binding of ET-1 to G-protein coupled receptor triggers aSignal Transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up regulation of ET-1. The enhanced ET-1 expression associated with the activation of PKC occurs in early diabetes.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

2492

Reference:

Ref: Yanagisawa, M. et al. Nature. 332, 411 (1988).

UNSPSC Code:

12352202