Following nutrient ingestion, both GLP-1, and Oxyntomodulin (OXM) are processed from proglucagon and secreted from the gut endocine L-cells. Oxyntomodulin (OXM) a 37-amino acid peptide hormone causes weight loss in humans and rodents. It activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence.
Proteins & Peptides
Peak Area by HPLC ≥95%
Pocai A. Mol Metab 3, 241 (2014), doi:10.1016/j.molmet.2013.12.001