£105.00
Estimated delivery Tue 30 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
71125-38-7
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
351.4
Alternative Names:
4-hydroxy-2-methyl-n-(5-methyl-2-thiazolyl)-1,1-dioxide-2h-1,2-benzothiazine-3-carboxamide, uh-ac 62xx
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective inhibitor of COX-2 (IC50s = 11.8 and 143 µM for COX-2 and COX-1, respectively, in an enzyme activity assay) and an NSAID; reduces croton oil-induced increases in TNF-α and IL-1β mRNA levels and increases IL-10 mRNA levels in cornea in a rabbit model of acute ocular inflammation at 0.03%; inhibits pleural plasma exudation in a carrageenan-induced rat model of pleurisy at 3 mg/kg; reduces PGE2 levels in plasma and right stifle joint synovial fluid in a canine model of unilateral osteoarthritis of the right stifle joint at 0.2 mg/kg
Storage Temperature:
-20°C
