£140.00
Estimated delivery Tue 7 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
78755-81-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
303.3
Alternative Names:
8-fluoro-5,6-dihydro-5-methyl-6-oxo-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester, ro 15-1788, ro 1722, ro 41-8157
- Data sheet: View or download
- MSDS: View or download
Product Description:
A GABAA receptor antagonist (IC50 = 2 nM in a radioligand binding assay using rat cortical synaptosomes); decreases the amplitude of electrically stimulated population spikes in rat hippocampal CA1 pyramidal neurons; increases the number of entries into the open arms of the elevated plus maze in BALB/c, but not C57BL/6, mice from 0.1-1,000 µg/kg; prevents allopregnanolone-induced reduction of burying behavior in ovariectomized rats at 5 and 10 mg/kg
Storage Temperature:
-20°C
