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Staurosporine

Supplier:
Catalogue number:
s7600-100 mg
Size:
100 mg
Product is available in:
  • UK
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£840.00 Estimated delivery Tue 28 Sep
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Alkaloid produced by Streptomyces, precursor in the synthesis of K252c; PKC and mammalian RNA splicing inhibitor.

Product Type:

Biochemicals

CAS Number:

62996-74-1

Alternative Names:

AM-2282

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

466.5

Reference:

Zhao C, Yin P, Mei C, et al. Down-regulation of DNA methyltransferase 3B in staurosporine-induced apoptosis and its mechanism in human hepatocarcinoma cell lines. Mol Cell Biochem. 2013 Apr;376(1-2):111-9. PMID: 23397112. Bruges G, Betancourt M, March M, et al. Apoptotic-like activity of staurosporine in axenic cultures of Trypanosoma evansi. Rev Inst Med Trop Sao Paulo. 2012 Mar-Apr;54(2):103-8. PMID: 22499424. Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919. Tanramluk D, Schreyer A, Pitt WR, et al. On the origins of enzyme inhibitor selectivity and promiscuity: a case study of protein kinase binding to staurosporine. Chem Biol Drug Des. 2009 Jul;74(1):16-24. PMID: 19519740.

Structure:

C28H26N4O3

Formula:

C28H26N4O3

UNSPSC Code:

12352200

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