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Haloperidol

Supplier:
Catalogue number:
h0142-1 g
Size:
1 g
Product is available in:
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£53.00 Estimated delivery Tue 28 Sep
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Butyrophenone; σ2 agonist, α1-adrenergic, D2, 5-HT2A, σ1 antagonist.

Product Type:

Biochemicals

CAS Number:

52-86-8

Alternative Names:

Haldol, Halosten, Linton, Keselan, Aloperidin, Brotopon, Dozic.

Storage Temp:

Ambient

Compound Purity:

≥95%

Molecular Weight:

375.86

Reference:

Cobos EJ, del Pozo E, Baeyens JM. Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells. J Neurochem. 2007 Aug;102(3):812-25. PMID: 17419803. Colabufo NA, Berardi F, Contino M, et al. Antiproliferative and cytotoxic effects of some sigma2 agonists and sigma1 antagonists in tumour cell lines. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):106-13. PMID: 15322732. Seeman P, Tallerico T. Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol Psychiatry. 1998 Mar;3(2):123-34. PMID: 9577836. Schotte A, Janssen PF, Megens AA, et al. Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography. Brain Res. 1993 Dec 24;631(2):191-202. PMID: 7510574.

Structure:

C21H23ClFNO2

Formula:

C21H23ClFNO2

UNSPSC Code:

12352200

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