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Novobiocin Sodium

Supplier:
Catalogue number:
n5986-1 g
Size:
1 g
Product is available in:
  • UK
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£88.00 Estimated delivery Tue 28 Sep
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Aminocoumarin; bacterial DNA gyrase inhibitor.

Product Type:

Biochemicals

CAS Number:

1476-53-5

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

634.61

Reference:

Gunaherath GM, Marron MT, Wijeratne EM, et al. Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors. Bioorg Med Chem. 2013 Sep 1;21(17):5118-29. PMID: 23859777. Wu D, Zhang R, Zhao R, et al. A novel function of novobiocin: disrupting the interaction of HIF 1α and p300/CBP through direct binding to the HIF1α C-terminal activation domain. PLoS One. 2013 May 6;8(5):e62014. PMID: 23671581. Walsh TJ, Standiford HC, Reboli AC, et al. Randomized Double-Blinded Trial of Rifampin with Either Novobiocin or Trimethoprim-Sulfamethoxazole against Methicillin-Resistant Staphylococcus aureus Colonization: Prevention of Antimicrobial Resistance and Effect of Host Factors on Outcome. Antimicrobial agents and chemotherapy 1993 Jun;37(6):1334–42. PMID: 8328783. Maxwell A. The interaction between coumarin drugs and DNA gyrase. Mol Microbiol 1993;9(4):681–6. PMID: 8231802.

Structure:

C31H35N2NaO11

Formula:

C31H35N2NaO11

UNSPSC Code:

51102800

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