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Etoposide

Supplier:
Catalogue number:
e7657-25 mg
Size:
25 mg
Product is available in:
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£58.00 Estimated delivery Tue 28 Sep
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Podophyllotoxin derivative; topoisomerase II inhibitor.

Product Type:

Biochemicals

CAS Number:

33419-42-0

Alternative Names:

EPEG, Lastet, Vepesid

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

588.56

Reference:

Johnson TS, Terrell CE, Millen SH, et al. Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PMID: 24259502. Mir Mohammadrezaei F, Mohseni kouchesfehani H, Montazeri H, et al. Signaling crosstalk of FHIT, CHK2 and p38 in etoposide induced growth inhibition in MCF-7 cells. Cell Signal. 2013 Jan;25(1):126-32. PMID: 23000346. Yoo SH, Yoon YG, Lee JS, et al. Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells. Int J Oncol. 2012 Oct;41(4):1443-54. PMID: 22895528. Shin SY, Kim CG, Ko J, et al. Transcriptional and post-transcriptional regulation of the PKC delta gene by etoposide in L1210 murine leukemia cells: implication of PKC delta autoregulation. J Mol Biol. 2004 Jul 16;340(4):681-93. PMID: 15223313. Mizumoto K, Rothman RJ, Farber JL. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide. Mol Pharmacol. 1994 Nov;46(5):890-5. PMID: 7969076. Nissen NI, Dombernowsky P, Hansen HH, et al. The epipodophyllotoxin derivatives VM-26 and VP-16-213, 1976-1979, a review. Recent Results Cancer Res. 1980;74:98-106. PMID: 7003663. Marcon L, Zhang X, Hales BF, et al. Effects of chemotherapeutic agents for testicular cancer on rat spermatogonial stem/progenitor cells. J Androl. 2011 Jul-Aug;32(4):432-443. PMID: 21088230. Li Z, Sun B, Clewell RA, et al. Dose-response modeling of etoposide-induced DNA damage response. Toxicol Sci. 2014 Feb;137(2):371-384. PMID: 24241721. Zhang F, Koh GY, Hollingsworth J, et al. Reformulation of etoposide with solubility-enhancing rubusoside. Int J Pharm. 2012 Sep 15;434(1-2):453-459. PMID: 22698860.

Structure:

C29H32O13

Formula:

C29H32O13

UNSPSC Code:

12352200

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