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82410-32-0
≥95%
A crystalline solid
255.2
2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6h-purin-6-one, 2'-ndg, 2'-nor-2'-deoxyguanosine, 9-(1,3-dihydroxy-2-propoxymethyl)guanine, bw 759, dhpg, gcv, rs 21592
- Data sheet: View or download
- MSDS: View or download
An active metabolite of valganciclovir and an antiviral nucleoside derivative; reduces human, monkey, mouse, and guinea pig CMV replication in plaque reduction assays (EC50s = 1.3-70 µM); topical application decreases disease severity and corneal leukocyte infiltration in a cat model of ocular FHV-1 epithelial infection at 0.15%; prevents allograft histologic injury and NK and myeloid cell infiltration in a mouse model of murine CMV infection with renal transplantation at 15 mg/kg; induces tumor regression in a K-BALB murine sarcoma model using a mixed population of HSV TK positive or negative cells
-20°C
