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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
5786-21-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
326.8
Alternative Names:
8-chloro-11-(4-methyl-1-piperazinyl)-5h-dibenzo[b,e][1,4]diazepine, hf 1854
- Data sheet: View or download
- MSDS: View or download
Product Description:
An atypical antipsychotic; a partial agonist at the 5-HT1A receptor (Ki = 180 nM); binds to the 5-HT2A, 5-HT2C, 5-HT3, 5-HT6 and 5-HT7 receptors (Kis = 3.3, 13, 110, 4, and 21 nM, respectively); binds to histamine H1 and α1-adrenergic receptors (Kis = 2.1 and 23 nM, respectively); induces the release of glutamate and D-serine from astrocytes; reverses locomotor hyperactivity and deficits in prepulse inhibition of acoustic startle in a rat neonatal ventral hippocampal ibotenic lesion model of schizophrenia at 2.5 mg/kg per day
Storage Temperature:
-20°C