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Cyclopamine

Supplier:
Catalogue number:
c9710-100 mg
Size:
100 mg
Product is available in:
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£441.00 Estimated delivery Tue 28 Sep
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Steroidal jerveratrum alkaloid found in Veratrum; Smo inhibitor.

Product Type:

Biochemicals

CAS Number:

4449-51-8

Alternative Names:

11-Deoxyjervine, 11-Deoxojervine, HSDB 3505.

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

411.62

Reference:

Song M, Ou X, Xiao C, et al. Hedgehog signaling inhibitor cyclopamine induces apoptosis by decreasing Gli2 and Bcl2 expression in human salivary pleomorphic adenoma cells. Biomed Rep. 2013 Mar;1(2):325-329. PMID: 24648943. Xu L, Wang X, Wan J, et al. Sonic Hedgehog pathway is essential for neuroblastoma cell proliferation and tumor growth. Mol Cell Biochem. 2012 May;364(1-2):235-41. PMID: 22350753. Stanton BZ, Peng LF. Small-molecule modulators of the Sonic Hedgehog signaling pathway. Mol Biosyst. 2010 Jan;6(1):44-54. PMID: 20024066.

Structure:

C27H41NO2

Formula:

C27H41NO2

UNSPSC Code:

12352200

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