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Neomycin Sulfate

Supplier:
Catalogue number:
n1755-100 g
Size:
100 g
Product is available in:
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£210.00 Estimated delivery Tue 28 Sep
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Polycationic aminoglycoside; protein translation inhibitor, cation channel/receptor (P2X, TRPV1) blocker.

Product Type:

Biochemicals

CAS Number:

1405-10-3

Storage Temp:

Ambient

Compound Purity:

≥98%

Molecular Weight:

908.9

Reference:

Wang L, Pulk A, Wasserman MR, et al. Allosteric control of the ribosome by small-molecule antibiotics. Nat Struct Mol Biol. 2012 Sep;19(9):957-63. PMID: 22902368. Bongartz EV, Rettinger J, Hausmann R. Aminoglycoside block of P2X2 receptors heterologously expressed in Xenopus laevis oocytes. Purinergic Signal. 2010 Dec;6(4):393-403. PMID: 21437010. Aukema KG, Chohan KK, Plourde GL, et al. Small molecule inhibitors of yeast pre-mRNA splicing. ACS Chem Biol. 2009 Sep 18;4(9):759-68. PMID: 19634919. Anupam R, Denapoli L, Muchenditsi A, et al. Identification of neomycin B-binding site in T box antiterminator model RNA. Bioorg Med Chem. 2008 Apr 15;16(8):4466-70. PMID: 18329274. Kawamoto SA, Sudhahar CG, Hatfield CL, et al. Studies on the mechanism of inhibition of bacterial ribonuclease P by aminoglycoside derivatives. Nucleic Acids Res. 2008 Feb;36(2):697-704. PMID: 18084035. Raisinghani M, Premkumar LS. Block of native and cloned vanilloid receptor 1 (TRPV1) by aminoglycoside antibiotics. Pain. 2005 Jan;113(1-2):123-33. PMID: 15621372. Wright JM, Collier B. The effects of neomycin upon transmitter release and action. J Pharmacol Exp Ther. 1977 Mar;200(3):576-87. PMID: 191590.

Structure:

C23H46N6O13 3H2SO4

Formula:

C23H46N6O13 3H2SO4

UNSPSC Code:

12352200

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